The benzyl alcohol preservative has been linked to severe toxicity in this population, including a potentially fatal condition known as gasping syndrome. Newborns have immature metabolic pathways and cannot efficiently metabolize benzyl alcohol, leading to its accumulation and metabolic acidosis with respiratory failure in severe cases
These effects can happen more often with larger peptides, hydrophobic peptides, basic peptides, or solutions prepared at very high concentration
Furthermore, being complementary to CD, Raman spectroscopy is immune to the effects of light scattering, and can therefore be used for the analysis of proteins in micelles and other scattering media (Chi et al., 1998)
If you feel you are not getting enough vitamin B12 and want to add a daily supplement during pregnancy, always consult your doctor first
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Core Supplies for This Protocol The essentials for running any reconstituted injectable: cold storage, accurate syringes, alcohol prep pads, and metabolic tracking