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The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities

NEJM 2025;392:2001-2012 In line with several clinical practice guidelines, I have been recommending the subcutaneous route of semaglutide to patients with type 2 diabetes and established c

Although our study shows that federal policy change can help increase access to GLP-1s for heart disease, we still have a long way to go to ensure that patients can access and afford these medications as their clinical indications keep expanding, said first author Christopher Scannell, a nonresident scholar at the USC Schaeffer Institute and senior research associate at the USC Mann School of Pharmacy and Pharmaceutical Sciences

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Additionally, precautions may apply for patients with allergy history, asthma, pregnancy, lactation, renal concerns, or concurrent injectable therapy