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Overexpression of Rptor (a core component of mTORC1) in HMC-3 microglia blunted butyrates capacity to suppress ISR signaling and to restrain LD formation, establishing mTORC1 as the obligatory node in butyrate-mediated neuroprotection

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Research indicates that the drug slows down gastric emptying and may adversely affect digestive system functions

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