Metformin, a first-line oral medication, reduces glucose production in the liver and improves insulin sensitivity
Approved GLP-1 Agonists for Weight Loss Currently, there are two GLP-1R agonists approved for the treatment of obesity, Saxenda (liraglutide) and Wegovy (semaglutide) , both developed by Novo Nordisk and approved by the FDA in 2014 and 2021, respectively
Their reasoning includes the potentially significant systemic side effects of stopping semaglutide and the lack of evidence for a causative link between GLP-1 RAs and NAION
Physical activity stimulates peristalsis through mechanical vibration, increased blood flow to the gut, and activation of the parasympathetic nervous system
Bland food for some, extra spicy for others The extent of taste change is different for everyone, Munger says
Fiber Constipation is one of the most common side effects of GLP-1 medications, and fiber-rich foods are one of the best ways to manage it