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Pyruvate, -ketoglutarate, glutamate, and aspartate all stayed constant between the two groups (Figure 1)

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132 Although it does not bind ATG5 directly, E2F1 enhances its expression through intermediate regulatory pathways

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Tirzepatide (the active ingredient in Mounjaro) is a dual GIP/GLP-1 agonist that some studies suggest may be even more effective for weight loss

therefore, this requirement should only be interpreted as a cohort selection strategy rather than confirmation of sleep disorder diagnosis