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[DOI] [PubMed] [Google Scholar] 71.Bjerre Knudsen L, et al

Brunchmann et al

Studies showing meaningful effects generally used 1,000mg or more per day

This is a normal, expected adjustment and not a reason to avoid GLP-1 therapy

Because retatrutide has no approved label, no established contraindications, warnings, monitoring requirements, or dosing instructions exist outside a trial one reason obtaining it outside research is unsafe