Considering the plasticity of microglia in response to different microenvironment, we speculated that the inconsistency in changes of microglia activation and proinflammatory factors secretory was possibly due to different functional types of microglia
Despite being a relatively new class of medication, researchers conducted a comprehensive analysis on a significant population of nearly half a million adults with type 2 diabetes over a follow-up period of 7 years, providing valuable insights into the effectiveness and safety of GLP-1RA
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10.1146/annurev.pharmtox.46.120604.141043 12 ChenM.-l.YiL.ZhangY.ZhouX.RanL.YangJ.et al (2016)
The gut senses food and produces the incretins GLP-1 and GIP to tell the pancreas to get ready to take care of the calorie hit thats on its way
In a three-month study with 58 hypertensive patients, taking the anti-hypertensive drug nifedipine (a calcium channel blocker), the plasma levels of vasoconstrictor molecule endothelin-1 were significantly lowered by 9% after one month and by 16% after three months in the group taking 100 mg Pycnogenol compared to the placebo group ( compared to the placebo group
