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By facilitating the utilization of fatty acids for energy production, it may aid in burning stored fat, thereby contributing to weight management efforts when combined with a balanced diet and regular exercise regimen

doi: 10.1016/S0140-6736(21)01324-6 Summary Keywords glucagon, GLP-1, obesity, co-agonist, weight loss Citation Hope DCD, Vincent ML and Tan TMM (2021) Striking the Balance: GLP-1/Glucagon Co-Agonism as a Treatment Strategy for Obesity

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At the same time, people eligible for Medicaid coverage required more health care than what was expected

Key Takeaways Retatrutide (LY3437943) is an investigational weight loss medication developed by Eli Lilly Triple-agonist mechanism: First drug to activate GLP-1, GIP, and glucagon receptors simultaneously Phase 2 results: Up to 24.2% weight loss at 48 weeks (approximately 58 lbs for a 240-lb person) Not FDA-approved: Currently in Phase 3 clinical trials, expected approval in 20272028 How it differs: Outperforms semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound) in weight loss trials Access now: Clinical trials (free), compounding pharmacies, or research peptide vendors What Is Retatrutide