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In SAMP mice, which naturally exhibit accelerated aging and genome instability, Epitalon treatment stabilized chromatin structure, supporting a preventative mechanism rooted in epigenetic control and DNA repair [61] One of the most compelling cancer prevention models is the HER-2/neu transgenic mouse, engineered to spontaneously develop mammary tumors

By implementing a tiered screening strategy that incorporates in silico zebrafish modeling, high-throughput in vivo validation, and humanized/organoid reconfirmation, the zebrafish is increasingly recognized as a pivotal platform for the clinical translation of natural products

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Oestrogen Metabolism and Liver Detoxification Your liver processes oestrogen in two main phases