Indeed, it has been reasonably suggested that abnormal lipids, which are known to be antigenic (Kanter et al., 2006), might act as a trigger for an autoimmune response in the human ALD brain (Moser et al., 2007)
2015, PMID 25832905)
Central Nervous System Research Applications Standard rodent CNS protocols include middle cerebral artery occlusion (stroke model), controlled cortical impact (traumatic brain injury), cuprizone feeding (demyelination), and spinal cord compression
Others may notice more gradual benefits over the course of several days to a week, particularly if their deficiency is mild or symptoms developed slowly
Conclusions In patients with IC, therapy is not straightforward
If the tool only offers preset vial sizes, use a setup that matches your label rather than forcing a nearest value