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A key trigger for ferroptosis is the dysregulation of Fe 2+ metabolism, and under physiological conditions, intracellular iron homeostasis is tightly maintained to support normal functions

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TGF Beta value was significantly higher in the RAD group compared to the control group ( p 0.0001), and a significant decrease was observed in the RAD+LCAR and LCAR groups compared to the RAD group ( p 0.0001, for both) (Fig