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Regardless the importance of GST activity for cellular vitality and health, the GST gene cluster is a hotspot for DNA sequence mutations that leads to the expression of active but functionally different GST variant proteins

some protocols include 3-month-on / 6-week-off cycling

Kandarakov O, Belyavsky A, Semenova E

However, individuals with higher oxidative stress loads or specific health challenges may require adjusted dosing protocols

I also forgot to add about one good thing while using this is that I notice when I had pimples, it usually results in blemishes & dark spots

So that's exactly how our body is working