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Because the activity of this ingredient depends on the integrity of the copper-peptide coordination sphere, Copper Tripeptide-1 is typically introduced in the cool-down phase below roughly 40 degrees C to minimize thermal stress and oxidative loss

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[DOI] [PubMed] [Google Scholar] 103.Kurooka H, Kato K, Minoguchi S, Takahashi Y, Ikeda J, Habu S, Osawa N, Buchberg AM, Moriwaki K, Shisa H, Honjo T