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12 The cardiovascular benefits of liraglutide were confirmed by the Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results (LEADER) trial which reported lower cardiovascular mortality and morbidity (nonfatal myocardial infarction or stroke) in patients with type 2 diabetes treated with liraglutide 1.8 mg compared with placebo over a median follow up of 3.8 years

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It lowers blood sugar levels by increasing the release of insulin and decreasing the secretion of glucagon

Beyond pathogenic mutations, common genetic polymorphisms also affect BCAA metabolism