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Several pro-angiogenic factors are known to drive vascular growth including vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), platelet-derived growth factor (PDGF), angiopoietins (Angs), hepatocyte growth factor (HGF), transforming growth factor- (TGF-), and matrix metalloproteinases (MMPs)

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For pernicious anaemia or malabsorption conditions, intramuscular hydroxocobalamin injections are the standard treatment, usually given every 2-3 months after an initial loading regimen

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