Moreover, in models of ischemiareperfusion injury and in KEAP1-inactivated lung cancer, inhibition or genetic ablation of CoQ biosynthetic enzymes restored sensitivity to ferroptosis or radiotherapy 115,116 , underscoring the reliance of some cancer cells on an abundant CoQ pool for redox defense and survival
Figure A shows that serum IGF-1 levels were lowest in a moderate protein diet and highest in a Western diet
Human evidence: Moderate, based on Khavinson's geriatric clinical observations
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By neutralizing oxidative stress within these cells, glutathione helps them stay resilient and effective