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In terms of frequency, short-term high-frequency administration (e.g., once daily for 3 consecutive days) enables rapid initiation of therapeutic efficacy, whereas long-term administration once weekly or once every 2 weeks is sufficient to maintain stable improvements, which aligns with clinical practice requirements (Klinger et al., 2021)

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Toxicol Sci 91 , 365371, doi: 10.1093/toxsci/kfj165 (2006)

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This shift has turned GLP-1 therapy into one of the fastest-growing pharmaceutical categories in the world