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A representative loading control (actin/vinculin) is shown in each figure, with panels from Figs

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Complexity of intervention (Intervention) Any pharmacological treatment is considered a complex intervention [30]

In IBS, this equilibrium is disturbed, as dysbacteriosis, increased gut permeability, visceral hypersensitivity, and mucosal microinflammation are present

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These effects are partly mediated through the activation of Sirts and improved mitochondrial function