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Base-case and scenario analyses were conducted

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A severely degenerated rotator cuff in a 65-year-old with decades of wear will not become a healthy 25-year-old tendon

Bcl-2 associated athanogene 3 (BAG3) inhibits dimerization and activity of G6PD (62)

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This modification enhances NNTs affinity for its substrate NADP+, promoting NADPH synthesis, maintaining ironsulfur cluster homeostasis, lowering intracellular ferrous iron levels and lipid peroxidation, and thereby protecting tumor cells from ferroptosis (118)