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GSH is one of the body's principal antioxidant defense molecules, playing a crucial role in the detoxification of cytotoxic compounds and reactive oxygen species.10 Intracellular GSH concentrations differ among tissues, typically ranging from 1 to 10 mM, with the highest levels observed in the liver.11 Experimental supplementation of GSH in animal models has been shown to reduce hepatocyte apoptosis, lower plasma AST and ALT activities, and protect against microvascular reperfusion injury.12 Melatonin (Mel) is a hormone primarily secreted by the pineal gland, but it is also synthesized in various tissues, including the ovaries, retina, lens, bone marrow, and gastrointestinal tract.13 In the retina and gastrointestinal system, it plays roles in visual adaptation and oxidative protection, respectively

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Zhang, G

The ratio [GSH]/[GSSG] is thought to be around 100 for cells that are not under oxidative stress [41], and [GSH]/[GSSG] = 107.5 in our model cell

Notably, the degree of MI increase on the treatment side was significantly lower than that on the control side ( p = 0.004) (Fig

Two common culprits that often cause discomfort are skin allergies and fungal infections