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The peptides specific targeting of NNMT-expressing adipocytes allows for a localized metabolic shift without widespread systemic overstimulation, presenting a unique model for selective fat mass modulation studies

While the etiology of NTD is multifactorial, some studies have found that blood concentrations of homocysteine or holo-transcobalamin to be lower in NTD-affected infants and mothers compared to non-affected controls (reviewed in 59)

In one study, DHEA replacement therapy was found to decrease abdominal fat and boost insulin action in older adults

CKD = chronic kidney disease

Aromatase, also known as estrogen synthetase, is encoded by the CYP19A1 gene

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