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Efectos adversos comunes : Los efectos secundarios gastrointestinales son los ms frecuentes, especialmente durante el inicio del tratamiento o aumentos de dosis: Nuseas (reportadas en hasta 44% de pacientes con dosis de 2.4 mg) Vmitos Diarrea Estreimiento Dolor abdominal Estos efectos generalmente disminuyen con el tiempo y pueden minimizarse mediante titulacin gradual de la dosis

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27 Jul 2026 FDA finalizes three guidances to broaden cancer clinical trial eligibility The US Food and Drug Administration (FDA) Oncology Center of Excellence (OCE) has finalized a trio of guidance documents to promote greater participation and diversity in oncology clinical trials