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COVID-19 contagion is linked with massive increase of neutrophil infiltration into the lungs where the neutrophils can release the stored TGF-, being a strong chemokine-like molecule

Main risks are GI side effects (usually manageable by dose titration) and very rare pancreatitis or gallbladder issues (monitor for symptoms, get labs if warranted)

These results are promising for liver fat reduction, but they come from early-phase research

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Nassar M, Misra A, Bloomgarden Z (2024) Impact of treatment with GLP-1RAs on suicide attempts in adults persons with type 2 diabetes: a retrospective comparative effectiveness study based on a global TriNetX health research database

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