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Insulin and insulin secretagogues - adding tirzepatide to insulin or insulin secretagogues (e.g., sulfonylureas, meglitinides) increases the risk of hypoglycemia

No clinical oversight no prescriber, no dosing guidance, no monitoring for side effects or contraindications

The MBOAT7-TMC4 variant rs641738 increases risk of nonalcoholic fatty liver disease in individuals of European descent

No routine monitoring change is needed

It puts the onus entirely on the athlete under the principle of strict liability. This means you, the athlete, are 100% responsible for every single substance that enters your body

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