the strongest evidence supports NAD+ as a metabolic and cognitive support intervention rather than a guaranteed longevity drug
Previous work has reported relatively increased Firmicutes and Proteobacteria and decreased Bacteroidetes in mice on an HFD, regardless of concomitant obesity (weight gain was minimized using a RELM knockout mouse 78 ) 78,79
Vitamin B12 deficiency can cause pernicious anemia, fatigue, and nerve damage
However, since B-12 cannot be digested without intrinsic factor, it needs to be administered through regular injections if that is the case
Vitamin B12 is primarily sourced from meat, making deficiencies more common among: Vegans and vegetarians Busy and active mums Individuals recovering from surgery Those on weight loss journeys Regular injections throughout the year or a structured course of treatment can help restore and maintain your vitamin levels
WADA names AOD-9604 explicitly under S2.2.3 (Growth hormone, its analogs and fragments) on the 2026 Prohibited List, alongside the unmodified hGH 176-191 fragment