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The collaborators included Isaac Chiu, assistant professor of immunology at Harvard Medical School, who studies the interplay between nervous and immune systems

Predrag Sikiric at the University of Zagreb, with dozens of peer-reviewed publications on tissue healing and angiogenesis

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However, CD8+ T cell ablation did accelerate tumor growth in non-obese mice on the control diet and in tirzepatide-treated DIO mice, revealing a clear impairment of antitumor immunity in response to obesity which is reversible with tirzepatide ( Figure 2L-M )

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For instance, atrasentan, an ERA, reduced kidney outcome risk by 35% but was also associated with a non-significant increase in hospitalization for HF [16]