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The NCCIH (National Center for Complementary and Integrative Health) and systematic review bodies generally characterize the evidence on collagen peptides as preliminary but promising for specific outcomes including skin elasticity and joint comfort, with bone density outcomes needing additional large-scale replication

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Possible side effects may include feelings of nausea, episodes of vomiting, and instances of diarrhea, relatively common but usually diminish over time

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Simpson H, Savine R, Snksen P, Bengtsson B-A, Carlsson L, Christiansen JS, Clemmons D, Cohen P, Hintz R, Ho K, Mullis P, Robinson I, Strasburger C, Tanaka T, Thorner M