Disruptions in the intrinsic factor (IF) pathway, including impaired IF production due to autoimmune conditions (pernicious anemia), damage to the ileum from diseases like Crohns or celiac disease, or surgical resection of the ileum, can severely impair B12 absorption
When NNMT activity is high, fat cells become more efficient at lipogenesis, the process of creating and storing fat
If you are a vegan, you may wish to consider getting one of these injections to ensure that your body is operating at its optimum level
B12 is a cofactor for the enzyme, methylmalonyl-CoA mutase, which transforms methylmalonyl-CoA into succinyl-CoA, which the body can directly use in the Krebs cycle to produce ATP
E66.01 Morbid (severe) obesity due to excess calories E66.09 Other obesity due to excess calories E66.1 Drug-induced obesity E66.2 Morbid obesity with alveolar hypoventilation E66.3 Overweight E66.8 Other obesity E66.9 Obesity, unspecified Note: When coding for obesity, its advisable to document the patients Body Mass Index (BMI) using the appropriate Z codes (Z68.- series) to provide a comprehensive clinical picture
[DOI] [PubMed] [Google Scholar] 11.Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM
