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PLoS ONE 6 , e24014 (2011)
Courses were required to include evidence of dose escalation (i.e., multiple strengths) to reduce inclusion of very short or incomplete treatment attempts
Adverse Reactions Nausea, vomiting, abdominal cramps, diarrhea, and a "fishy" body odor can occur with doses of about 3 g/day
Sribanditmongkol.et al
Botox is designated as a US Food and Drug Administration (FDA) pregnancy category C medicine, meaning that there are no well controlled studies in pregnant women, so it should only be used during pregnancy if the benefits outweigh the potential risks, which is typically the sentiment nowadays
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