retatrutide ly3437943 parkinson's disease clinical trial Everyone's talking about GLP1s for weight loss but the research on stopped me in my tracks. It showed a 17x reduction in tumor volume for lung cancer models and a 14x Frontiers | GLP-1R in diabetes

Despite tirzepatide producing substantially greater average weight loss, it does not carry a meaningfully higher gastrointestinal burden in these pooled analyses

3 One study (an extension of the original STEP-1 trial) also showed that participants regained two-thirds of their weight after discontinuing semaglutide, suggesting that maintaining weight loss may require long-term use

By the time Knudsen returned from maternity leave in 1994, all of her former colleagues had left and the future of the GLP-1 project looked bleak

The pain was getting less, I was sleeping again, and starting to lift weights again

Those with severe gastrointestinal conditions, including gastroparesis: Given the drug's effects on gastric motility, individuals with gastroparesis or other severe upper gastrointestinal disorders may experience worsening symptoms

I'm not sure what word we want to use