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In alcohol-exposed hepatocytes, acetaldehyde-driven ER stress and Golgi fragmentation impair this secretory pathway, leading to intracellular retention of MHC I complexes within the ER, ER-Golgi intermediate compartment (ERGIC), or fragmented Golgi (55, 5860)

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12 Creatine also helps increase muscle mass and reduce body fat percentage, and it has been shown to enhance performance in short, high-intensity exercise