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[58] Drugs that inhibit or induce these enzymes can significantly alter melatonins pharmacokinetic profile and potentially affect therapeutic outcomes or increase the risk of adverse effects
The intranasal administration of GHK-Cu represents a novel approach aimed at overcoming the challenge of bypassing the blood-brain barrier, a common hurdle in traditional targeted neurotherapeutics [14-16]
This work was supported by Heilongjiang Key R&D Program (2022ZX06C24), Heilongjiang Province Natural Science Foundation Joint Guidance Project (LH2022H081), and the National Natural Science Foundation of China (82174477)
Pharmacol, Biochem Behav 104:10512 Forester BP, Zuo CS, Ravichandran C, Harper DG, Du F, Kim S, Cohen BM, Renshaw PF (2012) Coenzyme Q10 effects on creatine kinase activity and mood in geriatric bipolar depression
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