The two trials on oral GSH, conducted in Thai population by Arjinpathana and Asawanonda, and in Filipino women by Handog et al
Recall, estrogen levels begin to decline around 30 years of age in women [9, 10], so the clinical trials selected for presentation include participants who were aged 30 to over 65 years
Intracellular ROS are primarily produced by mitochondrial metabolism
It is known that endogenous levels of GHK peptide naturally decline with age, from roughly 200 ng/ml at age 20 to 80 ng/ml at age 60 [3], and studies have shown that GHK-Cu can reset gene expression of human cells to a healthier state, which has led to breakthroughs in tissue regeneration and wound healing [4, 5, 6]
induced by treatment with reduced glutathione and buthionine sulfoximine
Key Takeaway: Taking these together creates a "bottom-up" and "top-down" approach to wellness, addressing both the microbial balance in the gut and the oxidative health of individual cells