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the most frequently involved are GLP-1 agonists, metformin, and alpha-glucosidase inhibitors

They found that hearing in males that had lived or were living in Chile was significantly worse than that of males who had lived their entire lives on Easter Island, and that this difference was related to years lived in modern society

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Thus, the development of orally active small molecule GLP-1R modulators remains an attractive strategy and a few compounds have progressed to clinical trials 8

References [1] Bansal A, Simon MC

Front Cell Infect Microbiol