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In clinical research, chromium has been shown to increase insulin sensitivity, Levothyroxine (Synthroid, Others) Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption
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So when the barrier becomes more permeable, the proposed mechanism is straightforward: substances that should stay in the gut lumen bacterial fragments, undigested food particles, pathogens cross into deeper tissue and the bloodstream, where they can drive immune activation and an increased antigenic and toxic load
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