Managing these involves dose adjustments, supportive care, or temporary discontinuation if needed
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Oral NSAIDs should be used cautiously and only after discussion with your GP, particularly if you have cardiovascular disease, renal impairment, or gastrointestinal problems
A minor portion of the drug is metabolized in the liver by the cytochrome P450 enzymes (primarily CYP2E1) to the reactive and toxic APAP intermediate, N -acetyl-p-benzoquinone imine (NAPQI) (Patten et al
You can confidently use it without worrying about developing a reliance on the product