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Biological evaluation included in vitro cytotoxicity tests on HepG2, intestinal epithelial cell line (Caco-2), and dopaminergic neurons (Differentiated SH-SY5Y with 0.1% retinoic acid) cell lines, showing low cytotoxicity

However, in some cases, a medical professional may consider administering the drug in order to monitor the patient

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This can help people with hyperthyroidism because excess thyroid hormone production can lead to breakdown of bones and an increased risk of osteoporosis

Caution should be observed in the use of flumazenil in epileptic patients treated with benzodiazepines