Although the possibility of irAEs exists every time someone is treated with checkpoint inhibition, most patients do quite well
At the cellular level, OA is the result of an imbalance between anabolic and catabolic processes
Effect of Vitamin E and memantine on functional decline in alzheimer disease: the TEAM-AD VA cooperative randomized trial
The most common gastrointestinal side effects include: Nausea very common (may affect more than 1 in 10 people), most pronounced during the first 4-5 weeks Diarrhoea common (may affect up to 1 in 10 people) Vomiting common (may affect up to 1 in 10 people) Abdominal pain common (may affect up to 1 in 10 people) Constipation common (may affect up to 1 in 10 people) Dyspepsia and flatulence common (may affect up to 1 in 10 people) Whilst belching may occur, 'sulphur burps' are not specifically enumerated as a distinct adverse effect in the SmPC
If you snore heavily, wake up feeling unrested despite getting enough hours of sleep, experience daytime tiredness, or if your partner has noticed you gasping or stopping breathing during the night, it is worth speaking to your GP about a sleep study
Mostajeran F, Tehrani HG, Rahbary B