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Irisin improves BBB dysfunction in SAP rats by inhibiting MMP-9 via the ERK/NF-B signaling pathway

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2017, Tenchov et al 2024) which can reduce an individuals quality of life and lead to complications that overburden the healthcare system (Aina et al 2021)

MMP-9 is a substance that is secreted in the body and is found in the central nervous system, extracellular matrix, and serum

Treatment of lymphocytes with 1 g of the mitogen leads to an increase in gene expression of approximately 50% [37]

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