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Human evidence is strongest for topical skin applications, where controlled studies show improved healing and skin quality

Given that various chemical substances have been identified as neurotransmitters/neuromodulators in mammals, eliciting long-distance ionic responses that effectively mediate neurotransmission, identification of more systematic signaling molecules in the future would offer new insights into the complex systemic defense signaling in plants

Ascorbic Acid (Vitamin C): Vitamin C is essential for collagen synthesis, which plays a key role in maintaining skin elasticity and firmness

Antioxidants are important for the body to prevent oxidative damage

It also has anti-inflammatory properties

Note: indexed curves are used to compare medium-term scenario trajectories when full absolute volumes are not publicly disclosed