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Clinical trials show tirzepatide users lose 2022% of body weight over 68 weeks, compared to 1015% with semaglutide monotherapy

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"But GLP-1s work best as a partner to good nutrition and movement." In this story GLP-1 medications such as Ozempic and Mounjaro work partly by slowing how quickly food leaves your stomach, which helps you feel full for longer, and by acting on receptors in the brain to reduce appetite and cravings

Your doctor can evaluate alternative causes including other medications, mood disorders, hormonal imbalances, or relationship factors before attributing changes to Zepbound