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We describe these only as research context: the studies are conducted in laboratory and cell-culture systems, and nothing here should be read as a statement of effect in humans

One commenter further proposed revising the minimum requirements for obtaining an Overall Hospital Quality Star Rating

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Kulkarni A, Wilson DM: The involvement of DNA-damage and repair defects in neurological dysfunction

Am J Cardiol 2019;123:558-64

Regarding molecular mechanism of ROS against biomolecules, free species like NO , NO 2 , H 2 O 2 , and ONOO - can cross lipid membranes and carry signals across organelles, while other types of ROS have limited half-life or physical properties that contribute to damaging of other biological molecules