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N-Acetylcysteine rapidly replenishes central nervous system glutathione measured via magnetic resonance spectroscopy in human neonates with hypoxic-ischemic encephalopathy

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This involves suppression of hippocampal microglial activation and astrocytic hyperplasia, restoration of cytokine homeostasisshifting from a pro- to an anti-inflammatory milieuand enhancement of brain-derived neurotrophic factor (BDNF) expression and AMPA receptor functionality

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