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Frequently reported adverse effects include: Nausea (affecting a significant proportion of participants) Vomiting Diarrhoea Abdominal pain and discomfort Constipation Dyspepsia These effects are typically most pronounced during treatment initiation and dose escalation

Frequent vomiting, persistent nausea, or inability to maintain normal food intake should always be evaluated

Intracellular GSH is distributed in different compartments

Nonetheless, it also acknowledged that these agents remain underutilized in PTDM management due to limitation of transplant-specific evidence [15]

To assess drug release, we applied FITC-conjugated D-CuP hydrogel to the wounds and measured the fluorescence signal of the residual hydrogel at predetermined time intervals in darkness

Hormonal Overshoot Hormones involved in hunger and energy balance may temporarily overshoot baseline levels