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Free heme, even at 50100 M concentration, is a toxic molecule due to its ability to generate ROS (Gutteridge and Smith, 1988) catalyzing the oxidation of proteins, the formation of cytotoxic lipid peroxides via lipid peroxidation and damaging DNA (reviewed in Kumar and Bandyopadhyay, 2005)

The ability of GSH to act as a sulfur and cysteine source promotes the growth of Oenococcus oeni and malolactic fermentation in wine [94]

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