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Seek urgent medical attention if you experience thoughts of self-harm or suicide, severe depression preventing daily functioning, or any mental health crisis

Clogging up your coronary arteries with cholesterol is a leading cause of congestive heart failure (ischemic heart disease), but there are other causes (COPD, emphysema etc.)

BMC Genomics 22, 124

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At 72 weeks, all doses (6 mg, 12 mg, 36 mg) met the primary endpoint of superior body weight reduction versus placebo and achieved key secondary goals including 10%, 15%, and 20% weight loss and reduced waist circumference