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We are conscious of the limitations of the animal models [123], however in a clinical trial undertaken by this group to asses IGF-1 in liver function under cirrhosis with these same dosage (20 g/kg/day) no side effects were reported and liver function greatly increased [108]

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J Diabetes Investig 11(6):13881402

When protein and EAA intake fall short of what the body needs to support muscle protein synthesis, lean mass is broken down to fill the gap

Weight loss outcomes Pooled clinical data shows that subcutaneous semaglutide achieves somewhat greater HbA1c reductions than oral semaglutide at equivalent doses