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Glutathione binds metals and other toxins and transforms them into compounds that can be excreted in bile or urine

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Identification of genetic polymorphisms at the glutathione S -transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer

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This is compensated in vivo by a simultaneous attack of a cocktail of components (defensins, cathelicidins) that disrupt the membrane integrity