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Deterioration of the incretin effect leads to a decreased ability to secrete insulin and hyperglycemia, which may exacerbate insulin resistance [14]

During successful weight loss, muscle volume may decline while muscle composition, relative strength, insulin sensitivity, and movement efficiency improve

Human neuroimaging studies demonstrate that GLP-1RAs influence brain activity during food cognition, supporting a role in pre-ingestive satiation

The theoretical rationale is that lower peak concentrations reduce GI side-effect burden

Your doctor will order tests to monitor your kidney function and watch for this side effect while youre taking Trulicity

This can help preserve muscle and prevent constipation