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These medications can lead to a significant and clinically meaningful reduction in body weight when used in conjunction with lifestyle changes

GLP-1s (Glucagon-Like Peptide-1 receptor agonists) are prescription medications that mimic natural hormones that regulate appetite, digestion, and blood sugar

Beyond the gut, people who took GLP-1 medications were also more likely to be diagnosed with problems in their bones and joints, like arthritis and tendinitis, compared with people taking other medications to manage their blood sugar

Our natural GLP-1 lasts seconds to minutes in our bodies, whereas the (prescription GLP-1) medications last over a week, she notes

The First Wave: Older GLP-1 Medications Before semaglutide stole the spotlight, several other GLP-1 agonists were used primarily for diabetes management, with modest weight loss benefits